藥物靶點重組兔單克隆抗體

締碼生物創(chuàng)新性的兔重組單克隆抗體平臺，聚焦腫瘤免疫靶點，使用功能活性充分驗證的重組蛋白作為抗原免疫兔子，直接從陽性兔B細胞中克隆IgG，重組表達進行流式驗證。這一技術(shù)不僅大大縮短了研發(fā)的時間，也讓我們能夠直接獲得IgG的基因序列信息，而無需擔心雜交瘤細胞丟失。

DIMA mAbs優(yōu)勢

現(xiàn)貨供應(yīng)，覆蓋多個熱門腫瘤靶點：

已成功開發(fā)出5000+兔單抗產(chǎn)品，覆蓋500余種靶點。

應(yīng)用范圍廣泛：

產(chǎn)品均經(jīng)過ELISA或流式驗證，還可開發(fā)WB、IHC、IF、熒光標記等應(yīng)用。

高特異性、高親和力：

兔抗體基因庫具有更高多樣性，更高親和力，表位覆蓋更廣。

多種抗體類型：

兔單抗、人兔嵌合抗體、人源化抗體等。

成藥性高：

締碼基于單B細胞技術(shù)的兔單抗發(fā)現(xiàn)平臺開發(fā)出來的抗體成藥性高。

高性價比，定制靈活：

可提供多標簽、多種屬及大規(guī)格包裝定制。

B細胞種子庫高效篩選兔單抗

締碼生物擁有獨創(chuàng)的DIMA mAbs重組單克隆抗體開發(fā)平臺，可以在完成動物免疫后直接從外周血中獲取陽性B細胞并克隆抗體基因序列。從單只免疫動物中我們可以得到上萬個靶點結(jié)合陽性B細胞克隆，從中能夠更為高效的篩選出具有高特異性、高親和力重組單克隆抗體。

驗證數(shù)據(jù)展示

A) Flow cytometry data of serially titrated Rabbit anti-SIRPα monoclonal antibody (DME100008). The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used. B) Competition assay demonstrating DME100008 blockade of CD47 binding to THP-1 cells. IC50=30.88ng/ml.

Left: Western blot analysis of CD38 protein using Anti-CD38 antibody (Cat. DME100027) at 1:1000 dilution.

Right: Western blot analysis of CD48 protein using Anti-CD48 antibody (SKU# DME100043) at 1/1000 dilution.

Anti-CD27 antibody(DM59), Rabbit mAb (DME100059) at 10μg/ml staining CD27 in Raji cells by IHC (SKU# DME100059);B. DME100059 at 10μg/ml staining CD27 in human tonsil tissue by IHC (SKU# DME100059)

A: The scheme of Anti-BCMA BiTE molecule (Cat. DMB100003). B: Tumor cell killing assay.?

Affinity ranking of different Rabbit anti-CS1 mAb clones (DM9, DM10, DM11) by titration of different concentration onto Raji cells. The Y-axis represents the mean fluorescence intensity (MFI) while the X-axis represents the concentration of IgG used.

單克隆抗體

Monoclonal Antibodies

Anti-Mouse IgG antibody(7B12), Goat mAb

SKU: DME201006 Target: Mouse IgG

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Mouse IgG antibody(4F9), Goat mAb

SKU: DME201005 Target: Mouse IgG

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Mouse IgG antibody(1F9), Goat mAb

SKU: DME201004 Target: Mouse IgG

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Mouse IgG antibody(5A5), Goat mAb

SKU: DME201003 Target: Mouse IgG

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Mouse IgG antibody(5E12), Goat mAb

SKU: DME201002 Target: Mouse IgG

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Mouse IgG antibody(3B8), Goat mAb

SKU: DME201001 Target: Mouse IgG

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Human IgG antibody(1D9), Rabbit mAb

SKU: DME101018 Target: Human IgG

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Human IgG antibody(1E12), Rabbit mAb

SKU: DME101036 Target: Human IgG

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Human IgG antibody(6E12), Rabbit mAb

SKU: DME101035 Target: Human IgG

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Human IgG antibody(6C5), Rabbit mAb

SKU: DME101037 Target: Human IgG

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Human IgG antibody(5B4), Rabbit mAb

SKU: DME101034 Target: Human IgG

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Human IgG antibody(4A12), Rabbit mAb

SKU: DME101033 Target: Human IgG

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Human IgG antibody(3D11), Rabbit mAb

SKU: DME101032 Target: Human IgG

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Human IgG antibody(2H2), Rabbit mAb

SKU: DME101031 Target: Human IgG

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Human IgG antibody(2D9), Rabbit mAb

SKU: DME101030 Target: Human IgG

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Human IgG antibody(2D4), Rabbit mAb

SKU: DME101029 Target: Human IgG

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Human IgG antibody(1G9), Rabbit mAb

SKU: DME101028 Target: Human IgG

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-EGFP antibody(5F3), Rabbit mAb

SKU: DME101046 Target: EGFP

Application: WB, IP

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-GPNMB antibody(11G4), IgG1 Chimeric mAb

SKU: DMC101152 Target: GPNMB

Application: Flow Cyt

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-CD19 antibody(16B8), IgG1 Chimeric mAb

SKU: DMC101150 Target: CD19

Application: Flow Cyt

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-CD205 antibody(1D4), IgG1 Chimeric mAb

SKU: DMC101114 Target: CD205

Application: Flow Cyt

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-TIM-1 antibody(1G3), IgG1 Chimeric mAb

SKU: DMC101113 Target: TIM-1

Application: Flow Cyt

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-ADAMTS1 antibody(8A9), IgG1 Chimeric mAb

SKU: DMC101151 Target: ADAMTS1

Application: Flow Cyt

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-NCR1 antibody(2C10), IgG1 Chimeric mAb

SKU: DMC101112 Target: NCR1

Application: Flow Cyt

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-FLT3 antibody(19A5), IgG1 Chimeric mAb

SKU: DMC101110 Target: FLT3

Application: Flow Cyt

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-ANPEP antibody(26H2), IgG1 Chimeric mAb

SKU: DMC101149 Target: ANPEP

Application: Flow Cyt

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-FZD4 antibody(10E10), IgG1 Chimeric mAb

SKU: DMC101111 Target: FZD4

Application: Flow Cyt

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Biotinylated Anti-GPRC5D antibody(DM61), Rabbit mAb

SKU: DME100061B Target: GPRC5D

Application: ELISA,IHC

Price: 10μg ￥1030.00 ; 50μg ￥3380.00 ; 100 μg ￥6080.00 ; 500 μg ￥19880.00

Monoclonal Antibodies

Anti-Dxd antibody(1E6); Rabbit mAb

SKU: DME101027 Target: Dxd

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Dxd antibody(1A12); Rabbit mAb

SKU: DME101026 Target: Dxd

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Dxd antibody(1A5); Rabbit mAb

SKU: DME101025 Target: Dxd

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

Monoclonal Antibodies

Anti-Dxd antibody(1A1); Rabbit mAb

SKU: DME101024 Target: Dxd

Application: ELISA

Price: 10μg ￥690.00 ; 50μg ￥2280.00 ; 100 μg ￥4080.00 ; 500 μg ￥13280.00

2B4	4-1BB	4-1BB-L	SIRPα
B7-H3	BCMA	CD123	CD48
CD138	CD22	CD27	GITR Ligand
CD28	CD38	CD47	CS1
GPRC5D	CTLA-4	MSLN	TROP2
GITR	TIM3	B7-2	PSCA
NKp30	BTN3A1	DNAM1	B7-H2
CD40

藥物靶點重組兔單克隆抗體

DIMA mAbs優(yōu)勢

現(xiàn)貨供應(yīng)，覆蓋多個熱門腫瘤靶點：

應(yīng)用范圍廣泛：

高特異性、高親和力：

多種抗體類型：

成藥性高：

高性價比，定制靈活：

B細胞種子庫高效篩選兔單抗

熱門抗體靶點

驗證數(shù)據(jù)展示

單克隆抗體

登錄

現(xiàn)貨供應(yīng)，覆蓋多個熱門腫瘤靶點：