| Clone ID | DMC460 |
|---|---|
| Target | |
| Synonyms | CD334; JTK2; TKF |
| Host Species | Rabbit |
| Description | PE-conjugated Anti-FGFR4 antibody(DMC460), IgG1 Chimeric mAb |
| Delivery | Under Development |
| Uniprot ID | P22455 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
| Storage & Shipping | Store?at?2°C-8°C?for?6?months |
| Background | The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways; including cell proliferation; cell differentiation; cell migration; lipid metabolism; bile acid biosynthesis; vitamin D metabolism; glucose uptake; and phosphate homeostasis. This protein consists of an extracellular region; composed of three immunoglobulin-like domains; a single hydrophobic membrane-spanning segment; and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors; setting in motion a cascade of downstream signals; ultimately influencing mitogenesis and differentiation. [provided by RefSeq; Aug 2017] |
| Usage | Research use only |
| Conjugate | PE-conjugated |
| DIMA Disclaimer | All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scr |
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